Canada Research Chair in
Structural Systems Biology

Our laboratory uses a structural (CryoEM, X-ray crystallography, NMR) and molecular biology approach combined with biophysical assays to investigate the molecular aspects of attachment proteins of emerging pathogens and interactions with the host and other microbes.

Our projects

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Role of protein dynamics towards immune evasion

Proteins are often seen as rigid bodies, however, they experience a multitude of molecular motions occurring on various timescale. Can alteration of protein motions be a mechanism to promote immune evasion?

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How to engineer therapeutics using protein dynamics

If proteins (and protein-protein interactions) allow for conformational flexibility (or motions), can we exploit this property toward engineering better therapeutics?

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Host-pathogens interactions

Viral and fungal pathogens use a broad diversity of host-cell receptors to promote entry and invasion. We will define the structural, molecular and biophysical aspects of the host-pathogen interactome.


Institut de Biologie Intégrative et des Systèmes (IBIS)
Pavillon Charles-Eugène-Marchand
Université Laval
1030, Avenue de la Médecine
Québec (Québec), G1V 0A6


Phone: +1 (418) 656 2131
Fax: +1 (418) 948 5487

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