Canada Research Chair in
Structural Systems Biology

Our laboratory uses a structural (CryoEM, X-ray crystallography, NMR) and molecular biology approaches combined with biophysical assays to investigate the molecular aspects of attachment proteins of emerging pathogens and interactions with the host and other microbes.

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This is us!

Welcome to the Gobeil Team website.

We are located in the Institut de Biologie Intégrative et des Systèmes (IBIS), Pavillon Charles-Eugène-Marchand in the Department of Biochemistry, Microbiology and Bioinformatics @ Université Laval.

Our projects

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Role of protein dynamics towards immune evasion

Proteins are often seen as rigid bodies, however, they experience a multitude of molecular motions occurring on various timescale. Can alteration of protein motions be a mechanism to promote immune evasion?

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How to engineer therapeutics using protein dynamics

If proteins (and protein-protein interactions) allow for conformational flexibility (or motions), can we exploit this property toward engineering better therapeutics?

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Host-pathogens interactions

Viral and fungal pathogens use a broad diversity of host-cell receptors to promote entry and invasion of host cells. We will define the structural, molecular, and biophysical aspects of the host-pathogen interactome.

Address

Institut de Biologie Intégrative et des Systèmes (IBIS)
Pavillon Charles-Eugène-Marchand
Université Laval
1030, Avenue de la Médecine
Québec (Québec), G1V 0A6


Contacts

Email: sophie.gobeil@bcm.ulaval.ca
Phone: +1 (418) 656 2131
Fax: +1 (418) 948 5487

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