This is us!
Welcome to the Gobeil Team website.
We are located in the Institut de Biologie Intégrative et des Systèmes (IBIS), Pavillon Charles-Eugène-Marchand in the Department of Biochemistry, Microbiology and Bioinformatics @ Université Laval.
Our laboratory uses a structural (CryoEM, X-ray crystallography, NMR) and molecular biology approaches combined with biophysical assays to investigate the molecular aspects of attachment proteins of emerging pathogens and interactions with the host and other microbes.
This is us!
Welcome to the Gobeil Team website.
We are located in the Institut de Biologie Intégrative et des Systèmes (IBIS), Pavillon Charles-Eugène-Marchand in the Department of Biochemistry, Microbiology and Bioinformatics @ Université Laval.
Proteins are often seen as rigid bodies, however, they experience a multitude of molecular motions occurring on various timescale. Can alteration of protein motions be a mechanism to promote immune evasion?
If proteins (and protein-protein interactions) allow for conformational flexibility (or motions), can we exploit this property toward engineering better therapeutics?
Viral and fungal pathogens use a broad diversity of host-cell receptors to promote entry and invasion of host cells. We will define the structural, molecular, and biophysical aspects of the host-pathogen interactome.
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